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Ricovir L Tablet

Ricovir L Tablet
Ricovir L Tablet
Price And Quantity
  • 10
  • Pack/Packs
  • USD ($)
Product Specifications
  • General Medicines
  • Lamivudine + Tenofovir
  • Tablets
  • Anti-Viral
  • HIV Patient
  • As Per Your Physician
  • 300mg + 300mg
  • 30 Pieces
  • At Normal Room Temperature
Product Description
Lamivudine (3TC, is a potent inhibitor of both HIV and HBV and was approved by the FDA for use in chronic HBV infection in1998. Lamivudine is already commonly prescribed as an antiretroviral agent in the treatment of HIV (although at a higher dose of 150mg bd or 300mg od), and can be used as part of a HAART regimen for patients with dual infection. A retrospective analysis of HBV infected patients within the CAESAR study (lamivudine +/- loviride added to zidovudine) demonstrated a significant reduction in HBV DNA levels during 52 weeks in those patients on lamivudine (40% HBV DNA <400 copies/ml) and an HBeAg loss of 20%3.
 
The elevated HBV DNA levels in HIV infected patients may potentially lead to a higher incidence of HBV resistant virus. This is well recognised to occur in immuno competent patients. Mutations associated with lamivudine are more rapidly selected in patients with HBV/HIV co-infection with an incidence rate of 50% and 90%, after 2 and 4 years, respectively4,5,6. 
 
Resistant virus emerges through the development of mutations within the highly conserved YMDD motif around the catalytic site of reverse transcriptase, analogous to the M184V mutation in lamivudine-resistant HIV. Patients with these mutations continue to show partial suppression of HBV DNA levels and there is evidence that improvement in transaminases and histological changes may continue to occur although seroconversion becomes less likely. 
 
Having learnt the lessons of nucleoside monotherapy in HIV disease there is increasing interest in the use of dual agents in the HBV/HIV setting. 
Trade Information
  • Surat
  • Paypal, Western Union
  • 10 Per Day
  • 10 To 12 Business Days Days
  • Within a certain price range free samples are available
  • South America, North America, Central America, Australia
  • Gujarat
Contact Us

Shop No. 406, Sunshine Complex, Sudama Chowk, Mota Varacha, Surat, Gujarat, 394101, India
Phone :+918061881893